Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041540 | 1.00 | LMNA (0.50) | LMNAALDH1A1MAPK1HTTL3MBTL1 | |
| SCHEMBL3655561 | 1.00 | LMNA (0.50) | LMNAALDH1A1MAPK1HTTL3MBTL1 | |
| SCHEMBL4149626 | 0.86 | SMN1; SMN2 (0.54) | ALDH1A1L3MBTL1CYP1A2CYP2D6HSD17B10 | |
| SCHEMBL8720900 | 0.86 | SMN1; SMN2 (0.54) | ALDH1A1L3MBTL1CYP1A2CYP2D6HSD17B10 | |
| SCHEMBL4279968 | 0.78 | FURIN (0.56) | LMNAALDH1A1MAPK1HTTL3MBTL1 | |
| SCHEMBL7968589 | 0.78 | FURIN (0.56) | LMNAALDH1A1MAPK1HTTL3MBTL1 | |
| SCHEMBL4037961 | 0.78 | FURIN (0.56) | LMNAALDH1A1MAPK1HTTL3MBTL1 | |
| SCHEMBL2067685 | 0.77 | FURIN (0.44) | LMNAALDH1A1MAPK1HTTATM | |
| SCHEMBL15053148 | 0.77 | CYP19A1 (0.50) | LMNAALDH1A1L3MBTL1POLBMAPT | |
| SCHEMBL2704783 | 0.77 | MEN1 (0.47) | LMNAALDH1A1MAPK1HTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118993945-A | Acetophenone hydrazone compound | 上海泰初化工技术有限公司 | 2024-11-22 | — | — | CN | claimed |
| WO-2023096448-A1 | USE OF OBATOCLAX IN TREATING METABOLIC AND FIBROTIC DISEASES | 에스케이케미칼 주식회사 | 2023-06-01 | — | — | WO | claimed |
| CN-116041345-A | Preparation method of compound with optical activity and hydantoin skeleton | 温州大学 | 2023-05-02 | — | — | CN | claimed |
| WO-2022165382-A1 | PHENYLETHYLIDENEHYDRAZINE COMBINATION THERAPIES | Neurawell Therapeutics (US) | 2022-08-04 | — | — | WO | claimed |
| WO-2021062048-A2 | METHODS AND SYSTEMS FOR MODULATING HEPATIC GABA PRODUCTION OR RELEASE TO ALTER FOOD INTAKE IN MONOGASTRIC SPECIES | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2021-04-01 | — | — | WO | claimed |
| WO-2020018779-A1 | USE OF PHENYLETHYLIDENEHYDRAZINE TO TREAT SEIZURE DISORDERS, DEVELOPMENTAL DISORDERS, NEUROLOGICAL DISORDERS, BEHAVIORAL DISORDERS AND ADDICTION | OVID THERAPEUTICS INC. (US) | 2020-01-23 | — | — | WO | claimed |
| US-20190167632-A1 | METHODS OF TREATING AND PREVENTING/REDUCING THE LIKELIHOOD OF MESIAL TEMPORAL LOBE EPILEPSY (TLE) | MUELLER WOLFGANG S (US) | 2019-06-06 | — | — | US | claimed |
| US-10123983-B2 | DNA methyltransferases for the treatment and prevention of arthritis | WASHINGTON UNIVERSITY (US) | 2018-11-13 | — | — | US | claimed |
| US-20170071889-A1 | DNA METHYLTRANSFERASES FOR THE TREATMENT AND PREVENTION OF ARTHRITIS | WASHINGTON UNIVERSITY | 2017-03-16 | — | — | US | claimed |
| EP-2593104-A2 | METHODS OF TREATING AND PREVENTING/REDUCING THE LIKELIHOOD OF MESIAL TEMPORAL LOBE EPILEPSY (TLE) | Müller, Prof. Dr., Wolfgang (DE) | 2013-05-22 | — | — | EP | claimed |
| US-20120115919-A1 | METHODS OF TREATING AND PREVENTING/REDUCING THE LIKELIHOOD OF MESIAL TEMPORAL LOBE EPILEPSY (TLE) | THE REGENTS OF THE UNIVERSITY OF NEW MEXICO | 2012-05-10 | — | — | US | claimed |
| WO-2011011692-A2 | METHODS OF TREATING AND PREVENTING/REDUCING THE LIKELIHOOD OF MESIAL TEMPORAL LOBE EPILEPSY (TLE) | STC.UNM (US) | 2011-01-27 | — | — | WO | claimed |
| US-20050080260-A1 | Preparation of prodrugs for selective drug delivery | LUMINIDE | 2005-04-14 | — | — | US | claimed |
| CN-116041345-B | Preparation method of compound with optical activity and hydantoin skeleton | 温州大学 | 2025-10-03 | — | — | CN | disclosed |
| US-20250082589-A1 | PHENYLETHYLIDENEHYDRAZINE DIMERS AND METHODS OF USING SAME | Neurawell Therapeutics (US) | 2025-03-13 | — | — | US | disclosed |
| US-20250082589-A1 | PHENYLETHYLIDENEHYDRAZINE DIMERS AND METHODS OF USING SAME | Neurawell Therapeutics (US) | 2025-03-13 | — | — | US | disclosed |
| EP-0097620-A2 | Heat or pressure sensitive registration material | CIBA-GEIGY AG (CH) | 1984-01-04 | — | — | EP | disclosed |
| EP-0006693-A1 | N-substituted trialkylstannylhydrocarbylcarboxylic acid hydrazides, methods of their preparation and insecticide compositions containing them | UNIROYAL, INC. (US) | 1980-01-09 | — | — | EP | disclosed |
| US-4178382-A | INSECTICIDE FOR COTTON | UNIROYAL, INC. (US) | 1979-12-11 | — | — | US | disclosed |
| US-4016157-A | COLORING PLASTICS AND LACQUERS | CIBA-GEIGY CORPORATION (US) | 1977-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080260-A1 | Preparation of prodrugs for selective drug delivery | APEH, PAH, ALAD | LMNA 939/4885ALDH1A1 61/4885MAPK1 3847/4885 |
| US-20250082589-A1 | PHENYLETHYLIDENEHYDRAZINE DIMERS AND METHODS OF USING SAME | PNMT, DRD4, HTR5A | LMNA 4398/4885ALDH1A1 1225/4885MAPK1 4306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.