Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 3/20 | 0.47 |
| ▸ | GABRD | O14764 | 3/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.47 |
| ▸ | GABRE | P78334 | 3/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.47 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.47 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.47 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.47 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isobutane SCHEMBL9414531 | 0.83 | GABRR1 (0.33) | GABRR1GABBR2GABBR1ALDH1A1 | |
| SCHEMBL7124651 | 0.83 | ALDH1A1 (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL166120 | 0.76 | — | — | |
| Acrylic Acid SCHEMBL14958549 | 0.74 | LMNA (0.40) | GABRR1GSRLMNABLMKMT2A | |
| SCHEMBL10881994 | 0.73 | — | — | |
| Formic Acid SCHEMBL10573322 | 0.73 | GABRR1 (0.30) | GABRR1 | |
| SCHEMBL8626766 | 0.73 | GABBR2 (0.33) | GABRR1GABBR2GABBR1 | |
| Succinic Acid SCHEMBL7086022 | 0.71 | GABRP (0.65) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Succinic Acid SCHEMBL27563645 | 0.71 | GABRP (0.65) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Succinic Acid SCHEMBL8397315 | 0.71 | EGLN1 (0.69) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827999-A1 | Detergents for hydrocarbon fuels | BP Chemicals (Additives) Limited (GB) | 1998-03-11 | — | — | EP | disclosed |