Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.36 |
| ▸ | XBP1 | P17861 | 3/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 3/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8726452 | 0.88 | MAPT (0.40) | MAPTNPSR1TDP1XBP1KDM4E | |
| SCHEMBL8728048 | 0.88 | CA1 (0.40) | TAS1R3TAS1R1KDM4EALDH1A1CA12 | |
| SCHEMBL8722057 | 0.81 | HRH3 (0.41) | MAPTNPSR1TDP1XBP1MAPK1 | |
| SCHEMBL8722967 | 0.80 | ALDH1A1 (0.41) | MAPTNPSR1TDP1XBP1MAPK1 | |
| SCHEMBL8722147 | 0.79 | CA2 (0.39) | TAS1R3TAS1R1KDM4ECA12CA1 | |
| SCHEMBL8727998 | 0.77 | TAS1R3 (0.46) | MAPTNPSR1TDP1XBP1TAS1R3 | |
| SCHEMBL8724198 | 0.77 | TAS1R3 (0.37) | MAPTNPSR1TAS1R3TAS1R1MAPK1 | |
| SCHEMBL8726226 | 0.76 | CA1 (0.49) | MAPTNPSR1KDM4EALDH1A1CA12 | |
| SCHEMBL8724211 | 0.72 | MAPT (0.41) | MAPTNPSR1TDP1XBP1MAPK1 | |
| SCHEMBL7717390 | 0.71 | MAPT (0.36) | MAPTNPSR1TDP1XBP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998035982-A1 | COMPOUNDS FOR USE IN ADEPT | ZENECA LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |