SCHEMBL8722239

SCHEMBL8722239

CC1c2ccccc2OPOc2cccc(C(C)(C)C)c21

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 1/20 0.39
CA2 P00918 1/20 0.32
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6237669 0.78 MAOA (0.37)
SCHEMBL4691813 0.77
SCHEMBL3353198 0.66 NR3C1 (0.41) GRM2CA2
SCHEMBL7785533 0.61 CA2 (0.35) CA2ALDH1A1TSHRTDP1
SCHEMBL30058027 0.60 ABCG2 (0.40) ALDH1A1TSHRTDP1
SCHEMBL2583969 0.60
SCHEMBL5177268 0.60 CA2 (0.38) CA2ALDH1A1TSHRTDP1
SCHEMBL367139 0.60 GRM2 (0.44) GRM2
SCHEMBL8853306 0.60 CA2 (0.38) CA2ALDH1A1TSHRTDP1
SCHEMBL436702 0.60 MAOA (0.58) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3947540-B1 METHOD FOR STABILIZING THERMOPLASTIC RECYCLATES, STABILIZED PLASTIC COMPOSITIONS, AND MOLDING COMPOUNDS AND MOLDED PARTS PRODUCED THEREFROM FRAUNHOFER GES FORSCHUNG (DE) 2023-08-16 EP disclosed
EP-0836635-A1 Compositions of synthetic polymers and a polysilane derivative Ciba SC Holding AG (CH) 1998-04-22 EP disclosed
WO-1997002322-A1 POLYSILANES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1997-01-23 WO disclosed