Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8726099 | 0.81 | PKM (0.41) | MGAMGAASIPKMMGAM2 | |
| SCHEMBL8722148 | 0.80 | CHRNB2 (0.41) | MGAMGAASIPKMMGAM2 | |
| SCHEMBL27958208 | 0.80 | CYP11B1 (0.54) | GAALMNAMAPTNPC1CYP1A2 | |
| SCHEMBL2179103 | 0.77 | APP (0.66) | MGAMGAASIPKMMGAM2 | |
| SCHEMBL8720919 | 0.76 | MAPT (0.46) | MGAMGAASIPKMMGAM2 | |
| SCHEMBL8722162 | 0.75 | PKM (0.36) | MGAMGAASIPKMMGAM2 | |
| SCHEMBL2627217 | 0.74 | IDO1 (0.59) | LMNAMAPTCYP3A4CYP2A6ALDH1A1 | |
| SCHEMBL11523469 | 0.74 | APP (0.61) | MGAMGAASIPKMMGAM2 | |
| SCHEMBL30469302 | 0.73 | PKM (0.52) | MGAMGAASIPKMMGAM2 | |
| SCHEMBL20557297 | 0.73 | PKM (0.52) | MGAMGAASIPKMMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998000430-A1 | IMIDAZOL DERIVATIVES USEFUL AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-08 | — | — | WO | disclosed |