Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720919 | 0.85 | MAPT (0.46) | PKMMGAMGAASIMGAM2 | |
| SCHEMBL8726099 | 0.82 | PKM (0.41) | PKMMGAMGAASIMGAM2 | |
| SCHEMBL8722148 | 0.81 | CHRNB2 (0.41) | PKMMGAMGAASIMGAM2 | |
| SCHEMBL8721417 | 0.79 | CYP11B1 (0.42) | GAASMN1; SMN2 | |
| SCHEMBL8722302 | 0.75 | MGAM (0.42) | PKMMGAMGAASIMGAM2 | |
| SCHEMBL8720915 | 0.72 | CYP17A1 (0.41) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6797025 | 0.71 | TSHR (0.53) | PKMMGAMGAASIMGAM2 | |
| SCHEMBL8722319 | 0.68 | MEN1 (0.42) | CYP3A4CYP2C9MEN1KMT2ALMNA | |
| SCHEMBL2627217 | 0.68 | IDO1 (0.59) | MAPTCYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL8724113 | 0.67 | CYP17A1 (0.42) | GAAMAPTCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998000430-A1 | IMIDAZOL DERIVATIVES USEFUL AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-08 | — | — | WO | disclosed |