Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.34 |
| ▸ | GLS | O94925 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8722753 | 0.79 | TRPV1 (0.34) | TRPV1GLSCHRNB2CHRNA4 | |
| SCHEMBL18790715 | 0.75 | CHRNB2 (0.53) | CHRNB2CHRNA4KDM4EALDH1A1 | |
| SCHEMBL27829815 | 0.71 | PHGDH (0.43) | RAB9AKDM4EMAPTLMNAALDH1A1 | |
| SCHEMBL22812290 | 0.70 | PANK3 (0.44) | RAB9ARETKDM4EMAPTLMNA | |
| SCHEMBL27702526 | 0.70 | SLC6A7 (0.52) | TRPV1PDGFRBERBB2RETFGFR1 | |
| SCHEMBL13801242 | 0.70 | CHRM2 (0.53) | RAB9APDGFRBERBB2RETFGFR1 | |
| SCHEMBL38663361 | 0.69 | CKS1B (0.49) | TRPV1RETMAPTLMNAALDH1A1 | |
| SCHEMBL11557829 | 0.69 | HTR2A (0.58) | RAB9AL3MBTL1KDM4EMAPTALDH1A1 | |
| SCHEMBL6371066 | 0.67 | HTR3A (0.68) | RAB9AKDM4EALDH1A1NPC1 | |
| SCHEMBL29544097 | 0.67 | HRH4 (0.47) | GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776936-A | Marcfortine/paraherquamide derivatives useful as antiparasitic agents | PHARMACIA & UPJOHN COMPANY (US) | 1998-07-07 | — | — | US | claimed |
| US-5776936-A | Marcfortine/paraherquamide derivatives useful as antiparasitic agents | PHARMACIA & UPJOHN COMPANY (US) | 1998-07-07 | — | — | US | disclosed |