SCHEMBL872315

SCHEMBL872315

COCCNC(=O)OC(F)(C(F)F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.35
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
GAA P10253 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
TP53 P04637 1/20 0.34
ALPL P05186 1/20 0.34
HDAC4 P56524 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
TDP1 Q9NUW8 2/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
BCHE P06276 1/20 0.32
KDM4E B2RXH2 1/20 0.32
GLA P06280 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL871157 0.83
SCHEMBL791556 0.73 TDP1 (0.56) MEN1KMT2AGAATDP1ALDH1A1
SCHEMBL21194949 0.73 ALDH1A1 (0.32) ALDH1A1
SCHEMBL872156 0.72 L3MBTL1 (0.35) HPGDMEN1KMT2AGAAL3MBTL1
SCHEMBL791894 0.70
SCHEMBL871733 0.70 HDAC4 (0.36) HDAC4
SCHEMBL871078 0.69 ACHE (0.40) MEN1KMT2AL3MBTL1TP53ALPL
SCHEMBL871772 0.68 MLYCD (0.47) GAA
SCHEMBL756889 0.67 ALDH1A1 (0.58) HPGDMEN1KMT2AL3MBTL1TP53
SCHEMBL871743 0.67 MLYCD (0.34) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2525433-B1 ELECTROLYTE CONTAINING AN AMIDE COMPOUND, AND ELECTROCHEMICAL DEVICE COMPRISING THE SAME LG CHEMICAL LTD (KR) 2016-12-07 EP claimed
US-8703345-B2 Electrolyte including amide compound and electrochemical device including the same LG CHEM, LTD. (KR) 2014-04-22 US claimed
EP-2525433-A2 ELECTROLYTE COMPRISING AN AMIDE COMPOUND, AND ELECTROCHEMICAL DEVICE COMPRISING THE ELECTROLYTE LG Chem, Ltd. (KR) 2012-11-21 EP claimed
US-20120077091-A1 ELECTROLYTE INCLUDING AMIDE COMPOUND AND ELECTROCHEMICAL DEVICE INCLUDING THE SAME LG CHEM, LTD. (KR) 2012-03-29 US claimed
EP-2525433-B1 ELECTROLYTE CONTAINING AN AMIDE COMPOUND, AND ELECTROCHEMICAL DEVICE COMPRISING THE SAME LG CHEMICAL LTD (KR) 2016-12-07 EP disclosed
US-8703345-B2 Electrolyte including amide compound and electrochemical device including the same LG CHEM, LTD. (KR) 2014-04-22 US disclosed
EP-2525433-A2 ELECTROLYTE COMPRISING AN AMIDE COMPOUND, AND ELECTROCHEMICAL DEVICE COMPRISING THE ELECTROLYTE LG Chem, Ltd. (KR) 2012-11-21 EP disclosed
US-20120077091-A1 ELECTROLYTE INCLUDING AMIDE COMPOUND AND ELECTROCHEMICAL DEVICE INCLUDING THE SAME LG CHEM, LTD. (KR) 2012-03-29 US disclosed