Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 2/20 | 0.50 |
| ▸ | CA5A | P35218 | 2/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30093387 | 0.88 | SMN1; SMN2 (0.50) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL24793189 | 0.88 | SMN1; SMN2 (0.50) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL38654908 | 0.82 | SMN1; SMN2 (0.62) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2697702 | 0.80 | ALDH1A1 (0.42) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL13844923 | 0.80 | ALDH1A1 (0.46) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL13847041 | 0.79 | ALDH1A1 (0.54) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL21126161 | 0.78 | MEN1 (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL10971819 | 0.78 | GAA (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL31194929 | 0.78 | ALDH1A1 (0.58) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL13861685 | 0.78 | ALDH1A1 (0.79) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2640724-A1 | NOVEL INDOLIZINE DERIVATIVES, AND PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2013-09-25 | — | — | EP | claimed |
| US-20130245006-A1 | NOVEL INDOLIZINE DERIVATIVES, AND PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2013-09-19 | — | — | US | claimed |
| WO-2012066234-A9 | NOVEL INDOLIZINE DERIVATIVES, AND PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-11-01 | — | — | WO | claimed |
| WO-2012066234-A1 | NOVEL INDOLIZINE DERIVATIVES, AND PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-05-24 | — | — | WO | claimed |
| EP-2640724-A1 | NOVEL INDOLIZINE DERIVATIVES, AND PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2013-09-25 | — | — | EP | disclosed |
| US-20130245006-A1 | NOVEL INDOLIZINE DERIVATIVES, AND PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2013-09-19 | — | — | US | disclosed |
| WO-2012066234-A9 | NOVEL INDOLIZINE DERIVATIVES, AND PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-11-01 | — | — | WO | disclosed |
| WO-2012066234-A1 | NOVEL INDOLIZINE DERIVATIVES, AND PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-05-24 | — | — | WO | disclosed |
| US-8138272-B2 | Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds | ELAN PHARMACEUTICALS, INC. (US) | 2012-03-20 | — | — | US | disclosed |
| US-8003769-B2 | Dye-labeled ribonucleotide triphosphates | APPLIED BIOSYSTEMS, LLC (US) | 2011-08-23 | — | — | US | disclosed |
| US-20100292457-A1 | Dye-labeled ribonucleotide triphosphates | APPLIED BIOSYSTEMS, LLC (US) | 2010-11-18 | — | — | US | disclosed |
| US-7678892-B2 | Dye-labeled ribonucleotide triphosphates | APPLIED BIOSYSTEMS, LLC (US) | 2010-03-16 | — | — | US | disclosed |
| US-20080031848-A1 | Preparation of Polymer Conjugates of Therapeutic, Agricultural, and Food Additive Compounds | ELAN PHARMACEUTICALS, INC. | 2008-02-07 | — | — | US | disclosed |
| US-20070293662-A1 | Dye-labeled ribonucleotide triphosphates | APPLERA CORPORATION (US) | 2007-12-20 | — | — | US | disclosed |
| WO-1994026738-A1 | N'-HETEROCYCLYL-N-BENZOFURANYL UREA DERIVATIVES AND THEIR ANALOGS AS ACAT INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080031848-A1 | Preparation of Polymer Conjugates of Therapeutic, Agricultural, and Food Additive Compounds | PIGO, MANBA, OAT | ALDH1A1 174/4885POLB 76/4885SMN1; SMN2 1142/4885 |
| US-20100292457-A1 | Dye-labeled ribonucleotide triphosphates | DUT, POLRMT, SAMHD1 | ALDH1A1 590/4885POLB 18/4885SMN1; SMN2 3432/4885 |
| US-20130245006-A1 | NOVEL INDOLIZINE DERIVATIVES, AND PREPARATION AND THERAPEUTIC USE THEREOF | INMT, TPH2, IDO2 | ALDH1A1 1356/4885POLB 2902/4885SMN1; SMN2 2550/4885 |
| US-20070293662-A1 | Dye-labeled ribonucleotide triphosphates | DUT, POLRMT, SAMHD1 | ALDH1A1 590/4885POLB 18/4885SMN1; SMN2 3432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.