Hydrochloric Acid

Hydrochloric Acid

SCHEMBL8723501

CCCCCCCC[N+](C)(CCCCCCCC)CCCCCCCC.O=C(OCCCCCCCCOc1ccccc1[N+](=O)[O-])c1ccccc1B(O)O.[Cl-]

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 2/20 0.43
SLC6A3 known ✓ Q01959 2/20 0.43
CHRM1 known ✓ P11229 1/20 0.43
CHRM3 known ✓ P20309 1/20 0.43
SLC6A2 known ✓ P23975 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.48
TSHR P16473 3/20 0.46
ALDH1A1 P00352 3/20 0.46
LMNA P02545 3/20 0.46
CYP3A4 P08684 2/20 0.45
TP53 P04637 1/20 0.45
MAPK1 P28482 1/20 0.45
KMT2A Q03164 4/20 0.43
NR1I2 O75469 2/20 0.43
OPRK1 P41145 2/20 0.43
HTR2B P41595 2/20 0.43
MLNR O43193 1/20 0.43
NR3C1 P04150 1/20 0.43
PGR P06401 1/20 0.43
ADRB2 P07550 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8721548 0.88 L3MBTL1 (0.56) L3MBTL1TSHRALDH1A1LMNAKMT2A
SCHEMBL8722482 0.88 L3MBTL1 (0.56) L3MBTL1TSHRALDH1A1LMNAKMT2A
SCHEMBL8725782 0.88 L3MBTL1 (0.56) L3MBTL1TSHRALDH1A1LMNAKMT2A
Hydrochloric Acid SCHEMBL8723502 0.82 L3MBTL1 (0.48) L3MBTL1ALDH1A1LMNAKMT2AKCNH2
SCHEMBL29000969 0.76 ALDH1A1 (0.70) L3MBTL1TSHRALDH1A1LMNACYP3A4
SCHEMBL9453026 0.76 ALDH1A1 (0.70) L3MBTL1TSHRALDH1A1LMNACYP3A4
SCHEMBL8724941 0.75 NPC1 (0.64) L3MBTL1ALDH1A1LMNAMAPK1KMT2A
SCHEMBL18012379 0.75 NPC1 (0.72) L3MBTL1ALDH1A1LMNACYP3A4MAPK1
SCHEMBL2304857 0.75 NPC1 (0.72) L3MBTL1ALDH1A1LMNACYP3A4MAPK1
SCHEMBL1123538 0.75 NPC1 (0.72) L3MBTL1ALDH1A1LMNACYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5800624-A LIPOPHILIC POLYMER, HYDROPHOBIC PLASTICIZER, QUATERNARY AMMONIUM OR PHOSPHONIUM CARRIER UNIVERSITY OF NOTRE DAME (US) 1998-09-01 US disclosed