Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15665561 | 0.96 | ALDH1A1 (0.44) | ALDH1A1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL15665799 | 0.96 | ALDH1A1 (0.44) | ALDH1A1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL489617 | 0.84 | SMN1; SMN2 (0.42) | ALDH1A1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL1806227 | 0.80 | SMN1; SMN2 (0.45) | ALDH1A1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL18281695 | 0.74 | KMT2A (0.43) | ALDH1A1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL696626 | 0.74 | CYP3A4 (0.40) | ALDH1A1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL4167580 | 0.71 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL6634962 | 0.71 | LMNA (0.46) | ALDH1A1FKBP1AMEN1KMT2AKDM4E | |
| SCHEMBL6285067 | 0.71 | CPB1 (0.44) | ALDH1A1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL12677552 | 0.70 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9ASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736518-A | Peptide compounds of (L) amino acids and ring molecules, and therapeutical applications thereof | POLIFARMA S.P.A. (IT) | 1998-04-07 | — | — | US | disclosed |
| US-5504071-A | HYPOTENSIVE AGENTS | POLIFARMA S.P.A. (IT) | 1996-04-02 | — | — | US | disclosed |