Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5250314 | 0.81 | PGK1 (0.42) | PGK1PGK2CES2CES1TRPA1 | |
| SCHEMBL8723919 | 0.75 | TSHR (0.48) | PGK1PGK2 | |
| SCHEMBL642404 | 0.72 | IDO1 (0.48) | — | |
| SCHEMBL2186969 | 0.71 | — | — | |
| SCHEMBL7305650 | 0.70 | PGK1 (0.35) | PGK1PGK2CES2CES1TRPA1 | |
| SCHEMBL28420 | 0.70 | SLC6A3 (0.37) | PGK1PGK2CES2CES1TRPA1 | |
| SCHEMBL384041 | 0.70 | ACP3 (0.46) | — | |
| SCHEMBL7305656 | 0.70 | LMNA (0.52) | — | |
| SCHEMBL20902925 | 0.70 | PGK1 (0.31) | PGK1PGK2CES2CES1TRPA1 | |
| SCHEMBL321883 | 0.70 | ACHE (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609058-B1 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO CO (JP) | 1998-12-09 | — | — | EP | disclosed |
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |
| EP-0609058-A2 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1994-08-03 | — | — | EP | disclosed |