Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720598 | 0.91 | NOS3 (0.42) | SLC6A4MAPTPOLBNOS3NOS1 | |
| SCHEMBL8725966 | 0.85 | HTR1F (0.46) | MAPTHTR1DHTR1AHTR2AHTR2C | |
| SCHEMBL8724218 | 0.85 | NOS3 (0.41) | SLC6A4MAPTPOLBNOS3NOS1 | |
| SCHEMBL7486116 | 0.83 | SLC6A4 (0.63) | SLC6A4NOS3NOS1 | |
| SCHEMBL8721895 | 0.81 | MAPT (0.42) | SLC6A4MAPTPOLBNOS3NOS1 | |
| SCHEMBL8382132 | 0.81 | HTR1D (0.40) | SLC6A4MAPTPOLBNOS3NOS1 | |
| SCHEMBL8385402 | 0.79 | MAPT (0.41) | MAPTPOLBNOS3NOS1STING1 | |
| SCHEMBL8387232 | 0.77 | SLC6A4 (0.55) | SLC6A4HTR1DDRD2HTR1A | |
| SCHEMBL8721897 | 0.77 | NOS3 (0.43) | SLC6A4MAPTNOS3NOS1DRD2 | |
| SCHEMBL8383659 | 0.76 | MAPT (0.43) | SLC6A4MAPTNOS3NOS1STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0875513-A1 | Substituted heteroaromatic 5-HT 1F agonists | ELI LILLY AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |