Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 13/20 | 0.46 |
| ▸ | HTR1D | P28221 | 6/20 | 0.41 |
| ▸ | HTR1B | P28222 | 5/20 | 0.41 |
| ▸ | HTR1A | P08908 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR1E | P28566 | 1/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 4/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8723863 | 0.85 | SLC6A4 (0.41) | HTR1DHTR1AHTR2AHTR2CMAPT | |
| SCHEMBL8724046 | 0.84 | HTR1F (0.44) | HTR1FHTR1DHTR1BHTR1APARP1 | |
| SCHEMBL30908995 | 0.79 | HTR1F (0.54) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL30909115 | 0.78 | HTR1F (0.54) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL8724225 | 0.78 | HTR1F (0.54) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL8720598 | 0.77 | NOS3 (0.42) | HTR1AHTR2AHTR2CMAPT | |
| SCHEMBL8385333 | 0.77 | HTR1F (0.40) | HTR1FHTR1DHTR1BHTR1APARP1 | |
| SCHEMBL8385462 | 0.76 | HTR1F (0.62) | HTR1FHTR1DHTR1BHTR1AHTR2A | |
| SCHEMBL8725956 | 0.76 | HTR1F (0.54) | HTR1FHTR1DHTR1BHTR1APARP1 | |
| SCHEMBL8721888 | 0.75 | HTR1F (0.39) | HTR1FHTR1DHTR1BHTR1ACDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |
| EP-0875513-A1 | Substituted heteroaromatic 5-HT 1F agonists | ELI LILLY AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |