Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.45 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7549232 | 0.88 | TSHR (0.49) | TSHRJAK2ERCC5FEN1P2RX7 | |
| SCHEMBL2652860 | 0.83 | ALDH1A1 (0.50) | TSHRJAK2ERCC5FEN1CES2 | |
| SCHEMBL29952517 | 0.83 | CES2 (0.60) | TSHRERCC5FEN1CES2CES1 | |
| SCHEMBL293634 | 0.83 | CES2 (0.60) | TSHRERCC5FEN1CES2CES1 | |
| SCHEMBL9178892 | 0.81 | MAPK1 (0.39) | TSHRCES2CES1ALDH1A1KMT2A | |
| Water SCHEMBL10353121 | 0.81 | CES2 (0.58) | TSHRERCC5FEN1CES2CES1 | |
| SCHEMBL2865994 | 0.80 | CYP1A2 (0.50) | TSHRCES2CES1ALDH1A1PKM | |
| SCHEMBL27512032 | 0.80 | P2RX7 (0.41) | TSHRP2RX7CES2CES1ALDH1A1 | |
| SCHEMBL21949122 | 0.80 | P2RX7 (0.43) | TSHRP2RX7TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7549234 | 0.79 | TSHR (0.55) | TSHRJAK2ERCC5FEN1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849783-A | Autobiotics and their use in eliminating nonself cells | CELL RESEARCH CORPORATION (US) | 1998-12-15 | — | — | US | disclosed |
| EP-0537267-B1 | AUTOBIOTICS AND THEIR USE IN ELIMINATING NONSELF CELLS IN VIVO | CELL RES CORP (US) | 1994-09-28 | — | — | EP | disclosed |
| EP-0537267-A1 | AUTOBIOTICS AND THEIR USE IN ELIMINATING NONSELF CELLS IN VIVO. | CELL RES CORP (US) | 1993-04-21 | — | — | EP | disclosed |
| US-5147652-A | Alpha ketoaldehydes | CELL RESEARCH CORPORATION (US) | 1992-09-15 | — | — | US | disclosed |
| WO-1992000727-A1 | AUTOBIOTICS AND THEIR USE IN ELIMINATING NONSELF CELLS IN VIVO | CELL RESEARCH CORPORATION (US) | 1992-01-23 | — | — | WO | disclosed |