Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18002876 | 0.85 | P2RX3 (0.61) | L3MBTL1CYP1A2CYP2C19GABRA2GABRB2 | |
| SCHEMBL5345436 | 0.85 | RAB9A (0.56) | CYP1A2CYP2C19GABRA2GABRB2P2RX3 | |
| SCHEMBL4229129 | 0.84 | SMN1; SMN2 (0.47) | L3MBTL1CYP1A2CYP2C19P2RX3SMN1; SMN2 | |
| SCHEMBL18003044 | 0.84 | P2RX3 (0.49) | L3MBTL1CYP1A2CYP2C19GABRA2GABRB2 | |
| SCHEMBL16398928 | 0.83 | KDM4E (0.57) | L3MBTL1CYP1A2CYP2C19CYP2C9SMN1; SMN2 | |
| SCHEMBL8726514 | 0.82 | PTGER2 (0.46) | L3MBTL1P2RX3SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9236648 | 0.81 | ICAM1 (0.46) | L3MBTL1CYP1A2CYP2C19CYP2C9P2RX3 | |
| SCHEMBL2328911 | 0.78 | L3MBTL1 (0.74) | L3MBTL1CYP1A2GABRA2GABRB2SMN1; SMN2 | |
| SCHEMBL23355309 | 0.77 | RAB9A (0.51) | CYP1A2CYP2C19P2RX3SMN1; SMN2MAPT | |
| SCHEMBL8722252 | 0.76 | MAPT (0.59) | L3MBTL1SMN1; SMN2MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700394-B1 | HERBICIDAL THIAZOLE DERIVATIVES | SHELL INT RESEARCH (NL) | 1998-04-01 | — | — | EP | disclosed |
| US-5693594-A | Herbicidal thiazole derivatives | AMERICAN CYANAMID COMPANY (US) | 1997-12-02 | — | — | US | disclosed |
| EP-0700394-A1 | HERBICIDAL THIAZOLE DERIVATIVES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027983-A1 | HERBICIDAL THIAZOLE DERIVATIVES | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1994-12-08 | — | — | WO | disclosed |