SCHEMBL8724484

SCHEMBL8724484

CC(=O)CC(=O)OCCn1c(=O)n(CCOC(=O)CC(C)=O)c(=O)n(CCOC(=O)CC(C)=O)c1=O

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.45
ALDH1A1 P00352 4/20 0.43
KDM4E B2RXH2 3/20 0.41
MGAM O43451 2/20 0.41
SI P14410 2/20 0.41
MGAM2 Q2M2H8 2/20 0.41
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
POLB P06746 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
ADORA2B P29275 2/20 0.36
MAPT P10636 2/20 0.34
GSK3A P49840 1/20 0.33
GSK3B P49841 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
PARG Q86W56 1/20 0.32
PLA2G4A P47712 1/20 0.32
GLA P06280 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23041374 0.92 DGKA (0.41) GAAALDH1A1KDM4EMGAMSI
SCHEMBL29420769 0.82 GAA (0.41) GAAALDH1A1KDM4EMEN1KMT2A
SCHEMBL7345266 0.80 KDM4E (0.42) GAAALDH1A1KDM4EMGAMSI
SCHEMBL19652445 0.80 GAA (0.66) GAAALDH1A1KDM4EMEN1KMT2A
SCHEMBL476436 0.80 GAA (0.43) GAAALDH1A1KDM4EMEN1KMT2A
SCHEMBL14587950 0.79 TSHR (0.33) GAAALDH1A1
SCHEMBL29227243 0.79 FOLH1 (0.37) GAAALDH1A1KDM4ETDP1
SCHEMBL17049401 0.77 GAA (0.53) GAAALDH1A1KDM4EMEN1KMT2A
SCHEMBL7350995 0.77 ALDH1A1 (0.42) GAAALDH1A1MGAMSIMGAM2
SCHEMBL2701579 0.76 GAA (0.60) GAAALDH1A1MGAMSIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11091651-B2 Acetoacetyl thermosetting resin for gel coat Polynt Composites USA, Inc. (US) 2021-08-17 US disclosed
US-20180094142-A1 ACETOACETYL THERMOSETTING RESIN FOR GEL COAT BNY MELLON CORPORATE TRUSTEE SERVICES LIMITED, AS SECURITY AGENT (GB) 2018-04-05 US disclosed
US-20180094142-A1 ACETOACETYL THERMOSETTING RESIN FOR GEL COAT BNY MELLON CORPORATE TRUSTEE SERVICES LIMITED, AS SECURITY AGENT (GB) 2018-04-05 US disclosed
US-20160108248-A1 Acetoacetyl Thermosetting Resin for Gel Coat Polynt Composites USA Inc. (US) 2016-04-21 US disclosed
US-20160108248-A1 Acetoacetyl Thermosetting Resin for Gel Coat Polynt Composites USA Inc. (US) 2016-04-21 US disclosed
US-20130233739-A1 Acetoacetyl Thermosetting Resin for Zero VOC Gel Coat CCP COMPOSITES US (US) 2013-09-12 US disclosed
US-20130233739-A1 Acetoacetyl Thermosetting Resin for Zero VOC Gel Coat CCP COMPOSITES US (US) 2013-09-12 US disclosed
EP-0881253-A1 B-ketoesters for use as polymer stabilisers AKCROS CHEMICALS (GB) 1998-12-02 EP disclosed