Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8725080 | 0.88 | CRHBP (0.48) | CRHBPCRHR2PTPN1ITGB1ITGA4 | |
| SCHEMBL7405135 | 0.77 | CRHBP (0.52) | CRHBPCRHR2PTPN1NR3C1MTNR1A | |
| SCHEMBL681077 | 0.77 | CYP2C19 (0.52) | — | |
| SCHEMBL681512 | 0.77 | CYP2C19 (0.52) | — | |
| SCHEMBL679845 | 0.77 | CYP2C19 (0.52) | — | |
| SCHEMBL2849432 | 0.75 | KYNU (0.48) | KMT2AMEN1TSHR | |
| SCHEMBL12774503 | 0.74 | CRHBP (0.54) | CRHBPCRHR2PTPN1NR3C1MTNR1A | |
| SCHEMBL5369549 | 0.73 | CRHBP (0.48) | CRHBPCRHR2PTPN1ITGB1ITGA4 | |
| SCHEMBL7403331 | 0.73 | CRHBP (0.48) | CRHBPCRHR2PTPN1NR3C1MTNR1A | |
| SCHEMBL8147928 | 0.72 | CRHBP (0.56) | CRHBPCRHR2PTPN1NR3C1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852195-A | Pyranone compounds useful to treat retroviral infections | PHARMACIA & UPJOHN COMPANY (US) | 1998-12-22 | — | — | US | disclosed |