Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.40 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CBLB | Q13191 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721042 | 0.90 | LMNA (0.49) | SMN1; SMN2RAB9ANPC1LMNAKMT2A | |
| SCHEMBL8725888 | 0.87 | CBLB (0.45) | RAB9ANPC1KLKB1KMT2AALDH1A1 | |
| SCHEMBL8721733 | 0.85 | BUB1 (0.43) | SMN1; SMN2RAB9ANPC1STIM1ORAI1 | |
| SCHEMBL8721044 | 0.85 | ALDH1A1 (0.46) | SMN1; SMN2RAB9ANPC1KMT2ASTIM1 | |
| SCHEMBL8725772 | 0.84 | CD38 (0.47) | SMN1; SMN2ALDH1A1CBLB | |
| SCHEMBL8725981 | 0.83 | XPO1 (0.40) | KMT2ASTIM1ORAI1PDE4BALDH1A1 | |
| SCHEMBL8720573 | 0.79 | KMT2A (0.39) | KMT2ASTIM1ORAI1ALDH1A1ADORA2A | |
| SCHEMBL8720597 | 0.79 | KMT2A (0.39) | RAB9AKMT2ASTIM1ORAI1PDE4B | |
| SCHEMBL8720745 | 0.79 | CHRNB2 (0.40) | KMT2AALDH1A1ADORA2AADORA1 | |
| SCHEMBL8721842 | 0.77 | ALDH1A1 (0.41) | SMN1; SMN2RAB9ANPC1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700391-B1 | HERBICIDAL COMPOUNDS | SHELL INT RESEARCH (NL) | 1998-10-21 | — | — | EP | claimed |