Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT2 | P34897 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547896 | 0.85 | DRD2 (0.37) | HRH3DRD2SLC6A4HTR1DHTR1B | |
| SCHEMBL8721866 | 0.82 | TP53 (0.38) | SHMT2HRH3MCHR1DRD2SLC6A4 | |
| SCHEMBL8723639 | 0.81 | KDM4E (0.40) | HRH3MCHR1DRD2SLC6A4HTR1D | |
| SCHEMBL8721868 | 0.80 | HRH3 (0.34) | SHMT2HRH3MCHR1DRD2SLC6A4 | |
| SCHEMBL8725933 | 0.80 | HTR1D (0.45) | SHMT2HRH3HTR1DHTR1BALDH1A1 | |
| SCHEMBL8720869 | 0.79 | ACHE (0.39) | SHMT2HRH3POLBHTR1DHTR1B | |
| SCHEMBL8721056 | 0.79 | MCHR1 (0.38) | HRH3MCHR1POLBKCNH2MAPT | |
| SCHEMBL8720774 | 0.79 | L3MBTL3 (0.43) | HRH3DRD2HTR1DHTR1BL3MBTL3 | |
| SCHEMBL8722156 | 0.78 | DRD2 (0.38) | HRH3DRD2SLC6A4HTR1DHTR1B | |
| SCHEMBL8721062 | 0.78 | LMNA (0.43) | HRH3HTR1DHTR1BL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |
| EP-0875513-A1 | Substituted heteroaromatic 5-HT 1F agonists | ELI LILLY AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |