Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 8/20 | 0.45 |
| ▸ | HTR1B | P28222 | 8/20 | 0.45 |
| ▸ | CDK4 | P11802 | 5/20 | 0.41 |
| ▸ | CCND3 | P30281 | 5/20 | 0.41 |
| ▸ | PTPRC | P08575 | 3/20 | 0.39 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720761 | 0.87 | TPSAB1 (0.43) | HTR1DHTR1BSMN1; SMN2 | |
| SCHEMBL8723639 | 0.86 | KDM4E (0.40) | HTR1DHTR1BALDH1A1HRH3 | |
| SCHEMBL8547892 | 0.84 | HTR1D (0.46) | HTR1DHTR1BPTPRCPTPN13L3MBTL1 | |
| SCHEMBL8721062 | 0.84 | LMNA (0.43) | HTR1DHTR1BLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL8720869 | 0.81 | ACHE (0.39) | HTR1DHTR1BSHMT2HRH3 | |
| SCHEMBL8723972 | 0.80 | HRH3 (0.35) | HTR1DHTR1BALDH1A1SMN1; SMN2SHMT2 | |
| SCHEMBL8725936 | 0.80 | SHMT2 (0.37) | HTR1DHTR1BALDH1A1L3MBTL1SHMT2 | |
| SCHEMBL8724094 | 0.79 | ACKR3 (0.39) | HTR1DHTR1BL3MBTL1HRH3 | |
| SCHEMBL8721795 | 0.79 | KMT2A (0.46) | ALDH1A1LMNASMN1; SMN2HRH3 | |
| SCHEMBL8725928 | 0.79 | RORC (0.47) | HTR1DHTR1BSMN1; SMN2L3MBTL1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |
| EP-0875513-A1 | Substituted heteroaromatic 5-HT 1F agonists | ELI LILLY AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |