Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | XBP1 | P17861 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8722057 | 0.91 | HRH3 (0.41) | ALDH1A1MAPTNPSR1RECQLL3MBTL1 | |
| SCHEMBL8726452 | 0.89 | MAPT (0.40) | ALDH1A1LMNAMAPTNPSR1TDP1 | |
| SCHEMBL8723006 | 0.85 | DHFR (0.33) | ALDH1A1LMNACYP1A2ALOX15CYP2C19 | |
| SCHEMBL8726507 | 0.84 | CA1 (0.47) | ALDH1A1LMNACYP1A2ALOX15CYP2C19 | |
| SCHEMBL8724211 | 0.81 | MAPT (0.41) | ALDH1A1MAPTNPSR1RECQLL3MBTL1 | |
| SCHEMBL8726160 | 0.80 | MAPT (0.36) | ALDH1A1MAPTNPSR1RECQLL3MBTL1 | |
| SCHEMBL8727998 | 0.77 | TAS1R3 (0.46) | ALDH1A1MAPTNPSR1RECQLTDP1 | |
| SCHEMBL8726187 | 0.77 | ADAMTS5 (0.36) | MAPTNPSR1RAB9A | |
| SCHEMBL8721920 | 0.76 | DHFR (0.34) | ALDH1A1LMNACYP1A2ALOX15CYP2C19 | |
| SCHEMBL30571505 | 0.74 | ALDH1A1 (0.50) | ALDH1A1LMNACYP2C19MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998035982-A1 | COMPOUNDS FOR USE IN ADEPT | ZENECA LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |