Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.31 |
| ▸ | TCF7L2 | Q9NQB0 | 5/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845439 | 0.90 | ALDH1A1 (0.38) | POLBALDH1A1MAOAMAOBNAMPT | |
| SCHEMBL872515 | 0.85 | PIK3CA (0.33) | POLBCFDMAOAMAOBNAMPT | |
| SCHEMBL13272255 | 0.83 | ALDH1A1 (0.33) | POLBALDH1A1MAOAMAOBNAMPT | |
| SCHEMBL873619 | 0.81 | TP53 (0.34) | ALDH1A1TSHRMEN1KMT2ABCHE | |
| SCHEMBL845370 | 0.79 | PIK3CA (0.37) | POLBCFDNAMPTMEN1KMT2A | |
| SCHEMBL873095 | 0.75 | HDAC8 (0.38) | POLBMAOAMAOBNAMPTBCHE | |
| SCHEMBL845354 | 0.75 | POLB (0.57) | POLBALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL873764 | 0.74 | TP53 (0.35) | — | |
| SCHEMBL845429 | 0.73 | CTSS (0.44) | POLBALDH1A1MAOAMAOBNAMPT | |
| SCHEMBL845682 | 0.73 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |