Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524815 | 0.81 | NPC1 (0.35) | GPR119NPC1CES2CES1KMT2A | |
| SCHEMBL8724282 | 0.77 | KMT2A (0.33) | KMT2AMEN1 | |
| SCHEMBL7574482 | 0.77 | HPGD (0.33) | KMT2AALDH1A1 | |
| SCHEMBL8490848 | 0.77 | NPC1 (0.36) | NPC1KMT2AALDH1A1L3MBTL1CASP3 | |
| SCHEMBL8754753 | 0.77 | POLB (0.34) | GPR119NPC1ALDH1A1 | |
| SCHEMBL8729992 | 0.76 | SMN1; SMN2 (0.36) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL8491100 | 0.76 | L3MBTL1 (0.40) | NPC1ALDH1A1L3MBTL1 | |
| SCHEMBL8489055 | 0.75 | NPC1 (0.34) | GPR119NPC1CES2CES1KMT2A | |
| SCHEMBL8729830 | 0.75 | CES2 (0.42) | NPC1CES2CES1KMT2AALDH1A1 | |
| SCHEMBL8726663 | 0.72 | HPGD (0.38) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625505-B1 | 2-Cyano-1,3-dione derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1998-10-28 | — | — | EP | disclosed |
| EP-0625505-A2 | 2-Cyano-1,3-dione derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-11-23 | — | — | EP | disclosed |