Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | F2R | P25116 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8724282 | 0.80 | KMT2A (0.33) | SMN1; SMN2KMT2AMEN1HPGDLMNA | |
| SCHEMBL8813402 | 0.79 | F2R (0.36) | F2RKMT2AMEN1MAPTRAB9A | |
| SCHEMBL8726663 | 0.78 | HPGD (0.38) | SMN1; SMN2KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL8726570 | 0.76 | GPR119 (0.34) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL7577840 | 0.74 | MAPK1 (0.37) | KMT2AMAPTRAB9AALDH1A1HPGD | |
| SCHEMBL7574482 | 0.72 | HPGD (0.33) | SMN1; SMN2KMT2AALDH1A1HPGD | |
| SCHEMBL8145611 | 0.72 | KMT2A (0.43) | SMN1; SMN2KMT2AMEN1MAPTRAB9A | |
| SCHEMBL25181502 | 0.71 | F2R (0.43) | SMN1; SMN2F2RKMT2ARAB9AALDH1A1 | |
| SCHEMBL30373676 | 0.71 | F2R (0.43) | SMN1; SMN2F2RKMT2ARAB9AALDH1A1 | |
| SCHEMBL9412825 | 0.70 | TSHR (0.53) | F2RKMT2AMEN1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625505-B1 | 2-Cyano-1,3-dione derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1998-10-28 | — | — | EP | disclosed |
| EP-0625505-A2 | 2-Cyano-1,3-dione derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-11-23 | — | — | EP | disclosed |