Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | DGKA | P23743 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3385884 | 0.88 | TSHR (0.44) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL8917298 | 0.85 | — | — | |
| SCHEMBL8724105 | 0.84 | ADRA2A (0.43) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL6560315 | 0.81 | MEN1 (0.55) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL20913720 | 0.81 | MEN1 (0.55) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL822271 | 0.81 | MEN1 (0.55) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL10726776 | 0.80 | CYP2C19 (0.47) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL243060 | 0.80 | ADRA2A (0.43) | ALDH1A1TSHRTP53HIF1AADRA2A | |
| SCHEMBL8919715 | 0.77 | ALDH1A1 (0.58) | ALDH1A1TSHRTP53HIF1AHSD17B10 | |
| SCHEMBL5344405 | 0.77 | TSHR (0.37) | ALDH1A1TSHRTP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5766960-A | Receptor membranes | AUSTRALIAN MEMBRANE AND BIOTECHNOLOGY RESEARCH INSTITUTE (AU) | 1998-06-16 | — | — | US | disclosed |