Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 4/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24768581 | 0.78 | ALDH1A1 (0.58) | ALOX5SMN1; SMN2LTA4HALDH1A1KMT2A | |
| SCHEMBL28016562 | 0.78 | ALDH1A1 (0.58) | ALOX5SMN1; SMN2LTA4HALDH1A1KMT2A | |
| SCHEMBL7666358 | 0.77 | LTA4H (0.52) | ALOX5SMN1; SMN2LTA4HALDH1A1MAPK1 | |
| SCHEMBL3978302 | 0.77 | ALOX5 (0.54) | ALOX5SMN1; SMN2LTA4HALDH1A1KMT2A | |
| SCHEMBL7769197 | 0.76 | ALOX5 (0.49) | ALOX5SMN1; SMN2LTA4HALDH1A1KMT2A | |
| SCHEMBL27493267 | 0.75 | ALDH1A1 (0.61) | ALOX5SMN1; SMN2ALDH1A1KMT2AMAPK1 | |
| SCHEMBL19862468 | 0.75 | ALOX5 (0.51) | ALOX5ALDH1A1KMT2AMAPK1TDP1 | |
| SCHEMBL3423094 | 0.74 | ALOX5 (0.51) | ALOX5SMN1; SMN2LTA4HALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL7773270 | 0.74 | ALOX5 (0.48) | ALOX5SMN1; SMN2LTA4HALDH1A1KMT2A | |
| SCHEMBL1713228 | 0.73 | ALOX5 (0.63) | ALOX5SMN1; SMN2LTA4HALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0813425-A4 | METAL RADIONUCLIDE LABELED PROTEINS FOR DIAGNOSIS AND THERAPY | NEORX CORP (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5756685-A | MEDICAL DIAGNOSIS; THERAPY | NEORX CORPORATION (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0813425-A1 | METAL RADIONUCLIDE LABELED PROTEINS FOR DIAGNOSIS AND THERAPY | NEORX CORPORATION (US) | 1997-12-29 | — | — | EP | disclosed |
| US-5556982-A | Metal radionuclide labeled proteins for diagnosis and therapy | NEORX CORPORATION (US) | 1996-09-17 | — | — | US | disclosed |
| WO-1995002423-A1 | METAL RADIONUCLIDE LABELED PROTEINS FOR DIAGNOSIS AND THERAPY | NEORX CORPORATION (US) | 1995-01-26 | — | — | WO | disclosed |
| US-5242679-A | Complexes for imaging tumors | NEORX CORPORATION (US) | 1993-09-07 | — | — | US | disclosed |
| US-5175343-A | For detection, radiotherapy and radeoimaging of tumors | NEORX CORPORATION (US) | 1992-12-29 | — | — | US | disclosed |
| US-5120526-A | Chelate compounds | NEORX CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |
| US-5037630-A | Chelated polypeptides specific for tumors, improved imaging | NEORX CORPORATION (US) | 1991-08-06 | — | — | US | disclosed |
| US-5021556-A | Method of radiolabeling chelating compounds comprising sulfur atoms with metal radionuclides | NEORX CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |
| US-4897255-A | Metal radionuclide labeled proteins for diagnosis and therapy | NEORX CORPORATION (US) | 1990-01-30 | — | — | US | disclosed |
| EP-0300431-A2 | Method of radiolabeling chelating compounds comprising sulfur atoms with metal radionuclides | NEORX CORPORATION (US) | 1989-01-25 | — | — | EP | disclosed |