Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | UGCG | Q16739 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.36 |
| ▸ | IL1RN | P18510 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8726245 | 0.90 | ACE (0.40) | ACERAB9AGAAUTS2RCTSK | |
| SCHEMBL8726548 | 0.88 | ALDH1A1 (0.43) | ALDH1A1LMNASMN1; SMN2RAB9AUTS2R | |
| SCHEMBL8728069 | 0.85 | SMN1; SMN2 (0.38) | ALDH1A1LMNASMN1; SMN2ACEUTS2R | |
| SCHEMBL8722093 | 0.82 | MAPT (0.47) | ALDH1A1LMNASMN1; SMN2RAB9AGAA | |
| SCHEMBL8722067 | 0.81 | CA1 (0.47) | ALDH1A1LMNASMN1; SMN2CA1CA12 | |
| SCHEMBL7715738 | 0.78 | CA1 (0.44) | ALDH1A1LMNASMN1; SMN2UTS2RCA1 | |
| SCHEMBL8511435 | 0.78 | BCHE (0.40) | ALDH1A1BCHEACHEPOLB | |
| SCHEMBL8812961 | 0.78 | BCHE (0.40) | ALDH1A1BCHEACHEPOLB | |
| SCHEMBL8722150 | 0.76 | CA2 (0.42) | ALDH1A1LMNASMN1; SMN2UTS2RCA2 | |
| SCHEMBL7717390 | 0.74 | MAPT (0.36) | ALDH1A1LMNASMN1; SMN2UTS2RCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998035982-A1 | COMPOUNDS FOR USE IN ADEPT | ZENECA LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |