Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | UGCG | Q16739 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 5/20 | 0.38 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | TACR1 | P25103 | 3/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8727972 | 0.90 | ALDH1A1 (0.43) | ACEGAARAB9AUGCGCTSK | |
| SCHEMBL8728069 | 0.85 | SMN1; SMN2 (0.38) | ACECTSKTAS1R3TAS1R1UTS2R | |
| SCHEMBL8722093 | 0.82 | MAPT (0.47) | GAARAB9A | |
| SCHEMBL8726548 | 0.78 | ALDH1A1 (0.43) | RAB9ATAS1R3TAS1R1UTS2R | |
| SCHEMBL7715738 | 0.78 | CA1 (0.44) | UTS2R | |
| SCHEMBL8726249 | 0.76 | LPAR1 (0.41) | RAB9A | |
| SCHEMBL8722150 | 0.76 | CA2 (0.42) | UTS2R | |
| SCHEMBL8722082 | 0.75 | CA1 (0.42) | CTSKCTSSTAS1R3TAS1R1CTSL | |
| SCHEMBL8722107 | 0.75 | PYGL (0.36) | UTS2R | |
| SCHEMBL8812961 | 0.74 | BCHE (0.40) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998035982-A1 | COMPOUNDS FOR USE IN ADEPT | ZENECA LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |