Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 5/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | HNF4A | P41235 | 2/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MAP2 | P11137 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28992365 | 0.83 | BCAT2 (0.44) | CSNK1EBCAT2KMT2AMEN1ALDH1A1 | |
| SCHEMBL28065801 | 0.80 | HNF4A (0.50) | FABP4ALDH1A1HNF4AACMSDKDM4E | |
| SCHEMBL15741932 | 0.75 | TSHR (0.45) | FABP4KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL8729082 | 0.74 | MYC (0.46) | BCAT2KMT2AALDH1A1HNF4AMAPT | |
| SCHEMBL30728189 | 0.74 | CYP1A2 (0.46) | FABP4BCAT2KMT2AMEN1GAA | |
| SCHEMBL8674376 | 0.71 | GABRP (0.42) | ALDH1A1KDM4EDHODH | |
| SCHEMBL10950361 | 0.71 | ALDH1A1 (0.41) | FABP4KMT2AALDH1A1HNF4AACMSD | |
| SCHEMBL31028133 | 0.70 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL39249 | 0.70 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL2875497 | 0.70 | FABP4 (0.51) | FABP4KMT2AALDH1A1HNF4AACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869782-A2 | METHODS OF TREATMENT WITH COMPOUNDS HAVING RAR $g(a)? RECEPTOR SPECIFIC OR SELECTIVE ACTIVITY | Vision Pharmaceuticals L.P. (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024116-A2 | METHODS OF TREATMENT WITH COMPOUNDS HAVING RARα RECEPTOR SPECIFIC OR SELECTIVE ACTIVITY | VISION PHARMACEUTICALS L.P. (US) | 1997-07-10 | — | — | WO | disclosed |