Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6205636 | 0.82 | NR4A2 (0.65) | KMT2AL3MBTL1MAPTMEN1HPGD | |
| SCHEMBL8729148 | 0.80 | NR4A2 (0.65) | KMT2AL3MBTL1MAPTMEN1HPGD | |
| SCHEMBL6205642 | 0.79 | NR4A2 (0.57) | KMT2AL3MBTL1MAPTMEN1HPGD | |
| SCHEMBL11606625 | 0.79 | ALDH1A1 (0.55) | KMT2AL3MBTL1MAPTMEN1HPGD | |
| SCHEMBL4826769 | 0.78 | NR4A2 (0.55) | KMT2AL3MBTL1MAPTMEN1HPGD | |
| SCHEMBL4495709 | 0.77 | KMT2A (0.69) | KMT2AL3MBTL1MEN1HPGDALDH1A1 | |
| SCHEMBL2282162 | 0.73 | KMT2A (0.53) | KMT2AMEN1HPGDALDH1A1HDAC1 | |
| SCHEMBL13545171 | 0.73 | KMT2A (0.49) | KMT2AMAPTMEN1HPGDALDH1A1 | |
| SCHEMBL135356 | 0.72 | NR4A2 (0.61) | KMT2AL3MBTL1MAPTMEN1HPGD | |
| SCHEMBL13337842 | 0.72 | KMT2A (0.51) | KMT2AMEN1HPGDALDH1A1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865439-A4 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS INC (US) | 1998-11-11 | — | — | EP | disclosed |
| EP-0865439-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1998-09-23 | — | — | EP | disclosed |
| WO-1996040672-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |