Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 15/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8758152 | 0.84 | ACACB (0.50) | ACACB | |
| SCHEMBL8729003 | 0.84 | ACACB (0.49) | ACACBITGB3ITGA2BHDAC8 | |
| SCHEMBL8729119 | 0.84 | ACACB (0.49) | ACACBITGB3ITGA2BHDAC8 | |
| SCHEMBL8732286 | 0.84 | ACACB (0.49) | ACACBITGB3ITGA2BHDAC8 | |
| SCHEMBL8729155 | 0.82 | NAMPT (0.43) | — | |
| SCHEMBL8729115 | 0.78 | ADRB3 (0.49) | ACACBITGB3ITGA2BHDAC8 | |
| SCHEMBL8729106 | 0.78 | ADRB3 (0.49) | ACACBITGB3ITGA2BHDAC8 | |
| SCHEMBL8727043 | 0.78 | SLC6A4 (0.43) | ACACB | |
| SCHEMBL8733840 | 0.78 | CTSK (0.40) | ACACBHDAC8 | |
| SCHEMBL8729117 | 0.76 | HDAC8 (0.47) | ACACBITGB3ITGA2BHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726165-A | HYPOGLYCEMIC AGENTS; DIETETICS; GASTROINTESTINAL DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-03-10 | — | — | US | disclosed |