Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 5/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733375 | 0.84 | KDM4E (0.41) | KDM4ETDP1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL8733133 | 0.84 | ABCB1 (0.47) | KDM4ELMNAC5AR1MEN1KMT2A | |
| SCHEMBL8734022 | 0.69 | CYP2D6 (0.52) | — | |
| SCHEMBL30628484 | 0.65 | C5AR1 (0.49) | KDM4ETDP1LMNARAB9AC5AR1 | |
| SCHEMBL9434444 | 0.65 | C5AR1 (0.55) | KDM4ETDP1LMNARAB9AC5AR1 | |
| SCHEMBL23403561 | 0.64 | RAB9A (0.50) | KDM4ETDP1RAB9AMEN1KMT2A | |
| SCHEMBL30880062 | 0.63 | ABCB1 (0.48) | LMNARAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL28534985 | 0.63 | ABCB1 (0.48) | LMNARAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL23432064 | 0.63 | ABCB1 (0.48) | LMNARAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL21634023 | 0.63 | ADRB2 (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726165-A | HYPOGLYCEMIC AGENTS; DIETETICS; GASTROINTESTINAL DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-03-10 | — | — | US | disclosed |