Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GLI1 | P08151 | 1/20 | 0.38 |
| ▸ | GLI2 | P10070 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 4/20 | 0.35 |
| ▸ | ACACA | Q13085 | 4/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733140 | 0.84 | KDM4E (0.42) | KDM4ELMNARAB9ATDP1ALDH1A1 | |
| SCHEMBL8728061 | 0.80 | ADRB2 (0.49) | RAB9AADRB2ADRB1 | |
| SCHEMBL8734022 | 0.72 | CYP2D6 (0.52) | ADRB2ADRB1 | |
| SCHEMBL8733133 | 0.66 | ABCB1 (0.47) | KDM4ELMNAADRB2ADRB1 | |
| SCHEMBL24238655 | 0.61 | TRPA1 (0.55) | KDM4ETDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11645394 | 0.61 | LTA4H (0.67) | — | |
| SCHEMBL12806626 | 0.60 | CETP (0.45) | — | |
| SCHEMBL5513626 | 0.60 | ALDH1A1 (0.38) | LMNARAB9AALDH1A1SMN1; SMN2 | |
| Methoxymethane SCHEMBL11646837 | 0.60 | LTA4H (0.59) | KDM4ESMN1; SMN2 | |
| SCHEMBL15087749 | 0.60 | HPGD (0.59) | LMNARAB9AALDH1A1SMN1; SMN2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726165-A | HYPOGLYCEMIC AGENTS; DIETETICS; GASTROINTESTINAL DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-03-10 | — | — | US | disclosed |