Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | APP | P05067 | 7/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2835024 | 0.85 | NR1H3 (0.58) | ALDH1A1APPHSD17B10MEN1MAPT | |
| SCHEMBL31085010 | 0.81 | ALDH1A1 (0.49) | ALDH1A1APPHSD17B10MEN1MAPT | |
| SCHEMBL17368742 | 0.79 | ALDH1A1 (0.50) | ALDH1A1APPHSD17B10MEN1MAPT | |
| SCHEMBL12552556 | 0.79 | ALDH1A1 (0.50) | ALDH1A1APPHSD17B10MEN1MAPT | |
| SCHEMBL9151953 | 0.76 | PPOX (0.47) | ALDH1A1HSD17B10MEN1KMT2ACASP3 | |
| SCHEMBL2399978 | 0.73 | ELANE (0.53) | ALDH1A1MEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL1783796 | 0.72 | APP (0.66) | ALDH1A1APPHSD17B10MEN1MAPT | |
| SCHEMBL10053401 | 0.71 | ALDH1A1 (0.59) | ALDH1A1APPHSD17B10MEN1MAPT | |
| SCHEMBL2616778 | 0.70 | APP (0.67) | ALDH1A1APPHSD17B10MEN1MAPT | |
| SCHEMBL23060308 | 0.69 | ALDH1A1 (0.47) | ALDH1A1APPHSD17B10MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639603-B1 | Polyphenylene ether with reactive end groups and thermoplastic composition containing them | ENICHEM SPA (IT) | 1998-09-30 | — | — | EP | claimed |
| EP-0639603-A1 | Polyphenylene ether with reactive end groups and thermoplastic composition containing them | ENICHEM S.p.A. (IT) | 1995-02-22 | — | — | EP | claimed |
| EP-0639603-B1 | Polyphenylene ether with reactive end groups and thermoplastic composition containing them | ENICHEM SPA (IT) | 1998-09-30 | — | — | EP | disclosed |
| EP-0639603-A1 | Polyphenylene ether with reactive end groups and thermoplastic composition containing them | ENICHEM S.p.A. (IT) | 1995-02-22 | — | — | EP | disclosed |