Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31085010 | 0.85 | ALDH1A1 (0.49) | NR1H3ALDH1A1HSD17B10MEN1MAPT | |
| SCHEMBL8733301 | 0.85 | ALDH1A1 (0.49) | NR1H3ALDH1A1HSD17B10MEN1MAPT | |
| SCHEMBL2741635 | 0.82 | LMNA (0.48) | NR1H3ALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL22021634 | 0.82 | LMNA (0.48) | NR1H3ALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL17368742 | 0.82 | ALDH1A1 (0.50) | NR1H3ALDH1A1HSD17B10MEN1MAPT | |
| SCHEMBL12552556 | 0.82 | ALDH1A1 (0.50) | NR1H3ALDH1A1HSD17B10MEN1MAPT | |
| SCHEMBL24671120 | 0.80 | MEN1 (0.44) | NR1H3ALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL10022401 | 0.79 | POLB (0.54) | NR1H3ALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL10022390 | 0.79 | KDM4E (0.63) | NR1H3ALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL19762359 | 0.78 | KDM4E (0.46) | NR1H3ALDH1A1LMNAHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240216516-A1 | GLUTARIMIDE-CONTAINING KRAS-MUTANT DEGRADER COMPOUNDS AND USES THEREOF | TIGER BIOTHERAPEUTICS INC. | 2024-07-04 | — | — | US | disclosed |
| US-20240217972-A1 | GLUTARIMIDE-CONTAINING PAN-KRAS-MUTANT DEGRADER COMPOUNDS AND USES THEREOF | TIGER BIOTHERAPEUTICS INC. | 2024-07-04 | — | — | US | disclosed |
| US-11530295-B2 | Hydrophilic polymer derivative having cyclic benzylidene acetal linker | NOF CORPORATION (JP) | 2022-12-20 | — | — | US | disclosed |
| US-20210062091-A1 | DIELECTRIC MATERIALS | MERCK PATENT GMBH (DE) | 2021-03-04 | — | — | US | disclosed |
| EP-3715340-A1 | PESTICIDALLY ACTIVE SEMI-CARBAZONES AND THIOSEMICARBAZONES DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-09-30 | — | — | EP | disclosed |
| US-20200291178-A1 | HYDROPHILIC POLYMER DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | NOF CORPORATION (JP) | 2020-09-17 | — | — | US | disclosed |
| US-20170260432-A1 | POLYARYLETHER KETONE IMIDE SULFONE ADHESIVES | THE BOEING COMPANY | 2017-09-14 | — | — | US | disclosed |
| US-8993585-B2 | Cyclic amine substituted pyrimidinediamines as PKC inhibitors | RIGEL PHARMACEUTICALS, INC. (US) | 2015-03-31 | — | — | US | disclosed |
| US-8399520-B2 | Selective estrogen receptor modulator | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2013-03-19 | — | — | US | disclosed |
| US-20120165322-A1 | RHO KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-28 | — | — | US | disclosed |
| US-20120165322-A1 | RHO KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-28 | — | — | US | disclosed |
| US-20120004315-A1 | Selective Estrogen Receptor Modulator | RADIUS HEALTH, INC. | 2012-01-05 | — | — | US | disclosed |
| US-20100130486-A1 | CYCLIC AMINE SUBSTITUTED PYRIMIDINEDIAMINES AS PKC INHIBITORS | RIGEL PHARMACEUTICALS, INC. | 2010-05-27 | — | — | US | disclosed |
| US-20100130486-A1 | CYCLIC AMINE SUBSTITUTED PYRIMIDINEDIAMINES AS PKC INHIBITORS | RIGEL PHARMACEUTICALS, INC. | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240216516-A1 | GLUTARIMIDE-CONTAINING KRAS-MUTANT DEGRADER COMPOUNDS AND USES THEREOF | KRAS, VHL, HRAS | NR1H3 3661/4885ALDH1A1 1085/4885LMNA 2689/4885 |
| US-20200291178-A1 | HYDROPHILIC POLYMER DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | H1-2, H1-0, H1-3 | NR1H3 2505/4885ALDH1A1 894/4885LMNA 3012/4885 |
| US-20100130486-A1 | CYCLIC AMINE SUBSTITUTED PYRIMIDINEDIAMINES AS PKC INHIBITORS | PRKCH, PKD2, PRKCQ | NR1H3 2925/4885ALDH1A1 3843/4885LMNA 1792/4885 |
| US-11530295-B2 | Hydrophilic polymer derivative having cyclic benzylidene acetal linker | H1-2, H1-0, H1-3 | NR1H3 2505/4885ALDH1A1 894/4885LMNA 3012/4885 |
| US-20240217972-A1 | GLUTARIMIDE-CONTAINING PAN-KRAS-MUTANT DEGRADER COMPOUNDS AND USES THEREOF | KRAS, VHL, HRAS | NR1H3 3559/4885ALDH1A1 1826/4885LMNA 2727/4885 |
| US-20120165322-A1 | RHO KINASE INHIBITORS | ROCK1, ROCK2, RHOA | NR1H3 909/4885ALDH1A1 2674/4885LMNA 1872/4885 |
| US-20120004315-A1 | Selective Estrogen Receptor Modulator | ESR1, GPER1, ESR2 | NR1H3 77/4885ALDH1A1 1214/4885LMNA 2894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.