Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733312 | 1.00 | KDM4E (0.46) | KDM4ECYP2D6MAPTALDH1A1TDP1 | |
| SCHEMBL8915382 | 0.83 | KDM4E (0.45) | KDM4ECYP2D6MAPTALDH1A1TP53 | |
| SCHEMBL8915385 | 0.83 | KDM4E (0.45) | KDM4ECYP2D6MAPTALDH1A1TP53 | |
| SCHEMBL13790221 | 0.82 | CYP2D6 (0.50) | KDM4ECYP2D6MAPTKMT2APIM1 | |
| SCHEMBL15362108 | 0.81 | CYP2D6 (0.46) | KDM4ECYP2D6MAPTALDH1A1TDP1 | |
| SCHEMBL15362109 | 0.81 | CYP2D6 (0.46) | KDM4ECYP2D6MAPTALDH1A1TDP1 | |
| SCHEMBL3464539 | 0.80 | TRPA1 (0.46) | CYP2D6MAPTALDH1A1TDP1KMT2A | |
| SCHEMBL3464533 | 0.80 | TRPA1 (0.46) | CYP2D6MAPTALDH1A1TDP1KMT2A | |
| SCHEMBL14813894 | 0.80 | ENPP2 (0.47) | PIM1PIM2GPR3FDPSMAOB | |
| SCHEMBL14814206 | 0.80 | ENPP2 (0.47) | PIM1PIM2GPR3FDPSMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672651-B1 | Process for the preparation of 4-fluoroalkoxycinnamonitriles | CLARIANT GMBH (DE) | 1998-12-09 | — | — | EP | claimed |
| US-5569776-A | Process for the preparation of 4-fluoroalkoxycinnamonitriles | HOECHET AG (DE) | 1996-10-29 | — | — | US | claimed |
| US-20230052528-A1 | TASPASE1 INHIBITORS AND USES THEREOF | UNIV CALIFORNIA (US) | 2023-02-16 | — | — | US | disclosed |
| WO-2021102359-A2 | TASPASE1 INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-05-27 | — | — | WO | disclosed |
| US-5569776-A | Process for the preparation of 4-fluoroalkoxycinnamonitriles | HOECHET AG (DE) | 1996-10-29 | — | — | US | disclosed |
| EP-0174769-B1 | ANTIFUNGAL AZOLE COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-11-21 | — | — | EP | disclosed |
| US-4925863-A | 1,3-DI(1,2,4-TRIAZOL-1-YL)-2-PROPANOL DERIVATIVES SUBSTITUTED WITH A STYRYL GROUP | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-15 | — | — | US | disclosed |
| EP-0174769-A1 | Antifungal azole compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230052528-A1 | TASPASE1 INHIBITORS AND USES THEREOF | RNASE1, TASP1, TPP1 | KDM4E 3697/4885CYP2D6 4100/4885MAPT 4555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.