SCHEMBL8733582

SCHEMBL8733582

N#Cc1ccc(Nc2c(F)c3c(c(F)c2Oc2c(Cl)cccc2Cl)C(=O)c2c(O)ccc(O)c2C3=O)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 1/20 0.39
TAS1R1 Q7RTX1 1/20 0.39
TAS1R2 Q8TE23 1/20 0.39
CXCR2 P25025 2/20 0.38
CYP11B1 P15538 2/20 0.36
TMPRSS4 Q9NRS4 1/20 0.34
STK10 O94804 1/20 0.33
SLK Q9H2G2 1/20 0.33
EGFR P00533 1/20 0.32
ERBB2 P04626 1/20 0.32
TOP2A P11388 1/20 0.32
TOP2B Q02880 1/20 0.32
LMNA P02545 2/20 0.32
MAPT P10636 2/20 0.32
TSHR P16473 1/20 0.32
HTT P42858 1/20 0.32
NLRP3 Q96P20 1/20 0.32
SALL4 Q9UJQ4 1/20 0.32
HSD17B1 P14061 1/20 0.32
HSD17B2 P37059 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8390198 0.87 TAS1R3 (0.40) TAS1R3TAS1R1TAS1R2CXCR2TMPRSS4
SCHEMBL7921180 0.85 CXCR2 (0.44) CXCR2CYP11B1STK10SLKTOP2A
SCHEMBL7933227 0.82 CXCR2 (0.46) CXCR2TMPRSS4TOP2ATOP2BLMNA
SCHEMBL7930796 0.79 CXCR2 (0.44) CXCR2TMPRSS4TOP2ATOP2BLMNA
SCHEMBL7930614 0.77 ADAMTS5 (0.40) CXCR2HTTKDM4E
SCHEMBL7933074 0.76 TBXA2R (0.38) CXCR2HTTKDM4ERAB9A
SCHEMBL6652489 0.75 MAPT (0.34) CXCR2CYP11B1STK10SLKTOP2A
SCHEMBL6652507 0.75 STK10 (0.39) CXCR2CYP11B1STK10SLKTOP2A
SCHEMBL7927152 0.73 MEN1 (0.40) EGFRMAPTMEN1POLBKMT2A
SCHEMBL7930030 0.73 CA12 (0.40) CXCR2EGFRLMNAMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0833203-A1 Color filter grade photosensitive resin coloring composition, and color filter using the same NIPPON SHOKUBAI CO., LTD. (JP) 1998-04-01 EP disclosed