SCHEMBL8733632

SCHEMBL8733632

O=C(O)CCOC(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.33
THRB P10828 1/20 0.33
ALKBH5 Q6P6C2 1/20 0.33
SUCNR1 Q9BXA5 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
APEX1 P27695 1/20 0.31
SLC22A6 Q4U2R8 1/20 0.31
ALDH1A1 P00352 1/20 0.30
RXRA P19793 1/20 0.30
RXRB P28702 1/20 0.30
RXRG P48443 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL6416238 0.98 THRB (0.32) LMNATHRBALKBH5SUCNR1EGLN1
SCHEMBL7053265 0.86 ALDH1A1 (0.44) LMNASLC22A6ALDH1A1
SCHEMBL11548111 0.83
SCHEMBL1681709 0.82 RXRA (0.30) RXRARXRB
SCHEMBL1080627 0.80 TET2 (0.39)
SCHEMBL1784668 0.77 LMNA (0.36) LMNAALKBH5SUCNR1EGLN1SLC22A6
SCHEMBL4613655 0.77 LMNA (0.40) LMNAALKBH5SUCNR1EGLN1SLC22A6
SCHEMBL5271852 0.75
Ammonia Solution, Strong SCHEMBL30988557 0.75
SCHEMBL21510518 0.73 ALDH1A1 (0.37) LMNAALKBH5SUCNR1EGLN1SLC22A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3131675-B1 RECOVERY OF BRANCHED FLUORINATED EMULSIFIERS 3M INNOVATIVE PROPERTIES CO (US) 2019-01-09 EP disclosed
US-9694333-B2 Recovery of branched fluorinated emulsifiers 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-07-04 US disclosed
EP-3131675-A1 RECOVERY OF BRANCHED FLUORINATED EMULSIFIERS 3M Innovative Properties Company (US) 2017-02-22 EP disclosed
US-20170028370-A1 RECOVERY OF BRANCHED FLUORINATED EMULSIFIERS 3M INNOVATIVE PROPERTIES COMPANY 2017-02-02 US disclosed
WO-2015160926-A1 RECOVERY OF BRANCHED FLUORINATED EMULSIFIERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-10-22 WO disclosed
EP-0692504-B1 Tetrafluoroethylene-ethylene copolymers with a core-shell particle structure DYNEON GMBH (DE) 1998-02-25 EP disclosed
US-5506281-A Copolymer of the tetrafluoroethylene-ethylene type having a core-shell particle structure HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-09 US disclosed
EP-0692504-A1 Tetrafluoroethylene-ethylene copolymers with a core-shell particle structure HOECHST AKTIENGESELLSCHAFT (DE) 1996-01-17 EP disclosed
EP-0491287-B1 Cross-linkable fluorinated copolymers and lacquers based on these copolymers HOECHST AG (DE) 1995-03-22 EP disclosed
EP-0276649-B1 Curable fluor-containing copolymers as binders in weatherproof coatings HOECHST AG (DE) 1993-11-03 EP disclosed
US-4604172-A Process for the electrolysis of sodium chloride HOECHST AKTIENGESELLSCHAFT (DE) 1986-08-05 US disclosed
US-4584343-A VINYL ESTERS, VINYL ALCOHOL, AND FLUOROOLEFIN POLYMER HOECHST AKTIENGESELLSCHAFT (DE) 1986-04-22 US disclosed
EP-0171696-A1 Method of electrolyzing sodium chloride HOECHST AKTIENGESELLSCHAFT (DE) 1986-02-19 EP disclosed
EP-0150430-A2 Cross-linkable fluorinated copolymers, lacquers based on these copolymers and their use HOECHST AKTIENGESELLSCHAFT (DE) 1985-08-07 EP disclosed
EP-0030663-B1 LAYER-MODIFIED PARTICULATED FLUOROPOLYMERS AND PROCESS FOR THEIR PREPARATION HOECHST AKTIENGESELLSCHAFT (DE) 1983-10-12 EP disclosed
US-4391940-A POLYMERS/SHELL-CORE/ HOECHST AKTIENGESELLSCHAFT (DE) 1983-07-05 US disclosed
EP-0002809-B1 FLUORISED THERMOPLASTIC POLYMER HOECHST AKTIENGESELLSCHAFT (DE) 1981-10-14 EP disclosed
EP-0030663-A2 Layer-modified particulated fluoropolymers and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1981-06-24 EP disclosed
US-4262101-A HOMOPOLYMER MODIFIED WITH HEXAFLUOROPROPYLENE AND PERFLUOROPROPYL PERFLUOROVINYL ETHER HOECHST AKTIENGESELLSCHAFT (DE) 1981-04-14 US disclosed
EP-0002809-A1 Fluorised thermoplastic polymer HOECHST AKTIENGESELLSCHAFT (DE) 1979-07-11 EP disclosed