SCHEMBL4613655

SCHEMBL4613655

O=C(O)CCOC(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.40
EGLN1 Q9GZT9 2/20 0.40
ALKBH5 Q6P6C2 1/20 0.40
SUCNR1 Q9BXA5 1/20 0.40
SLC22A6 Q4U2R8 1/20 0.36
TSHR P16473 4/20 0.35
NFKB1 P19838 1/20 0.35
PMP22 Q01453 1/20 0.35
ALDH1A1 P00352 1/20 0.34
FFAR3 O14843 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ACE P12821 1/20 0.33
SLC15A2 Q16348 1/20 0.32
MAPK1 P28482 1/20 0.32
SLC13A3 Q8WWT9 1/20 0.32
OR51E2 Q9H255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16028948 0.85 LMNA (0.46) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL20738800 0.83 TSHR (0.37) LMNAEGLN1ALKBH5SUCNR1SLC22A6
SCHEMBL2488500 0.81 ALDH1A1 (0.54) LMNASLC22A6TSHRNFKB1PMP22
SCHEMBL1784668 0.80 LMNA (0.36) LMNAEGLN1ALKBH5SUCNR1SLC22A6
SCHEMBL21510518 0.80 ALDH1A1 (0.37) LMNAEGLN1ALKBH5SUCNR1SLC22A6
SCHEMBL2871005 0.79
SCHEMBL31051710 0.77 TSHR (0.36) TSHRALDH1A1
SCHEMBL15541114 0.77 PDK2 (0.33) PMP22KMT2APDK2
SCHEMBL24107357 0.77 FFAR3 (0.39) LMNAEGLN1ALKBH5SUCNR1SLC22A6
SCHEMBL8733632 0.77 LMNA (0.33) LMNAEGLN1ALKBH5SUCNR1SLC22A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113874426-B Water-soluble film and package 株式会社可乐丽 2025-03-28 CN claimed
US-20250333902-A1 FLUORINE-CONTAINING COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2025-10-30 US disclosed
US-20250276924-A1 CHEMICAL AND BIOLOGICAL DEGRADATION OF ETHER PER- AND POLYFLUOROALKYL SUBSTANCES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-09-04 US disclosed
CN-113874426-B Water-soluble film and package 株式会社可乐丽 2025-03-28 CN disclosed
EP-4516773-A1 FLUORINE-CONTAINING COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2025-03-05 EP disclosed
WO-2024185687-A1 FLUORINE-CONTAINING COMPOUND ダイキン工業株式会社 2024-09-12 WO disclosed
WO-2023180189-A1 MPRO TARGETING ANTIVIRAL COMPOUNDS EXSCIENTIA AI LIMITED (GB) 2023-09-28 WO disclosed
WO-2022272036-A1 TEAD INHIBITORS AND USES THEREOF CEDILLA THERAPEUTICS, INC. (US) 2022-12-29 WO disclosed
CN-113874426-A Water-soluble film and package 株式会社可乐丽 2021-12-31 CN disclosed
WO-2020218321-A1 WATER-SOLUBLE FILM AND PACKAGING 株式会社クラレ 2020-10-29 WO disclosed
EP-3624797-A1 KINASE INHIBITORS AND USES THEREOF Denali Therapeutics Inc. (US) 2020-03-25 EP disclosed
WO-2018213632-A1 KINASE INHIBITORS AND USES THEREOF DENALI THERAPEUTICS INC. (US) 2018-11-22 WO disclosed
CN-108699106-A Novel trifluoromethyl propanamide derivative as HTRA1 inhibitor 豪夫迈·罗氏有限公司 2018-10-23 CN disclosed
EP-1549705-B1 FLUOROPOLYMER COMPOSITIONS 3M INNOVATIVE PROPERTIES CO (US) 2008-03-05 EP disclosed
EP-1549705-A1 FLUOROPOLYMER COMPOSITIONS 3M Innovative Properties Company (US) 2005-07-06 EP disclosed
US-6846880-B2 Composition comprising fluoropolymer including interpolymerized units derived from nitrogen-containing cure site monomer and amidine-containing curative, which is bis-amidine, tris-amidine, or tetra-amidine, or salt 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-01-25 US disclosed
WO-2004033546-A1 FLUOROPOLYMER COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-04-22 WO disclosed
US-20040072959-A1 Crosslinked elastomers using organonitrogen curing agents based on bis-amidine, tris-amidine, or tetra-amidine, or a salt thereof 3M INNOVATIVE PROPERTIES COMPANY 2004-04-15 US disclosed
CN-1309655-A Cyclic compounds useful in treatment of dyslipidaemia, atherosclerosis and diabetes, pharmaceutical compositions and preparation process MERCK PATENT GMBH (DE) 2001-08-22 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250276924-A1 CHEMICAL AND BIOLOGICAL DEGRADATION OF ETHER PER- AND POLYFLUOROALKYL SUBSTANCES PFAS, FGB, PFKFB1 LMNA 3630/4885EGLN1 456/4885ALKBH5 676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.