Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 3/20 | 0.39 |
| ▸ | ACACA | Q13085 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8729157 | 0.82 | ACACB (0.46) | ACACBACACA | |
| SCHEMBL8733831 | 0.78 | ACACB (0.45) | ACACBHDAC8 | |
| SCHEMBL507002 | 0.73 | MTNR1A (0.66) | CTSKCTSSATMMTNR1AMTNR1B | |
| SCHEMBL30241501 | 0.73 | MTNR1A (0.66) | CTSKCTSSATMMTNR1AMTNR1B | |
| SCHEMBL507001 | 0.73 | MTNR1A (0.66) | CTSKCTSSATMMTNR1AMTNR1B | |
| SCHEMBL25288585 | 0.72 | CTSS (0.55) | CTSKCTSSKMT2AATMMEN1 | |
| SCHEMBL8729143 | 0.72 | CYP2C9 (0.44) | CTSKCTSSATMHDAC8MTNR1A | |
| SCHEMBL25288584 | 0.72 | CTSS (0.55) | CTSKCTSSKMT2AATMMEN1 | |
| SCHEMBL8729136 | 0.72 | CYP2C9 (0.44) | CTSKCTSSATMHDAC8MTNR1A | |
| SCHEMBL8729117 | 0.72 | HDAC8 (0.47) | CTSKCTSSACACBATMHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726165-A | HYPOGLYCEMIC AGENTS; DIETETICS; GASTROINTESTINAL DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-03-10 | — | — | US | disclosed |