Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | JUN | P05412 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12929225 | 0.75 | JUN (0.56) | JUNNFKB1NFKB2RELACHRM5 | |
| SCHEMBL3278069 | 0.73 | POLB (0.56) | GSK3AGSK3BJUNNFKB1NFKB2 | |
| SCHEMBL2184752 | 0.72 | CA12 (0.44) | JUNNFKB1NFKB2RELAIDO1 | |
| SCHEMBL15093852 | 0.70 | CES2 (0.43) | JUNNFKB1NFKB2RELACHRM5 | |
| SCHEMBL8730226 | 0.69 | CCR6 (0.48) | MGLLFAAHJUNNFKB1NFKB2 | |
| SCHEMBL146412 | 0.69 | MGLL (1.00) | MGLLFAAHGSK3AGSK3BPTGS1 | |
| SCHEMBL17123177 | 0.69 | MGLL (0.52) | MGLLFAAHGSK3AGSK3BPTGS1 | |
| SCHEMBL20804327 | 0.69 | MGLL (0.52) | MGLLFAAHGSK3AGSK3BPTGS1 | |
| SCHEMBL6407334 | 0.69 | CYP2D6 (0.54) | TSHRKDM4ECYP3A4CYP2D6USP2 | |
| SCHEMBL25993044 | 0.69 | JUN (0.49) | JUNNFKB1NFKB2RELACHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722959-B1 | Highly oxygen-permeable heat-resistant material | MENICON CO LTD (JP) | 1998-04-08 | — | — | EP | disclosed |
| US-5587445-A | Highly oxygen-permeable heat-resistant material | MENICON CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0722959-A2 | Highly oxygen-permeable heat-resistant material | Menicon Co., Ltd. (JP) | 1996-07-24 | — | — | EP | disclosed |