Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | JUN | P05412 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | DAO | P14920 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12340322 | 0.87 | MAPT (0.40) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL2184970 | 0.84 | CA12 (0.54) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL12340315 | 0.82 | CMA1 (0.42) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL12340316 | 0.77 | MAPT (0.52) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL19660075 | 0.73 | KDM4E (0.44) | KDM4EHTTSMN1; SMN2TSHRCYP2D6 | |
| SCHEMBL12895972 | 0.73 | SRC (0.50) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL8734091 | 0.72 | MGLL (0.52) | KDM4EHTTSMN1; SMN2IDO1JUN | |
| SCHEMBL55686 | 0.71 | P2RX3 (0.49) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL5531705 | 0.71 | ADRB1 (0.40) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL12150059 | 0.70 | CA12 (0.56) | CA12CA1CA2CA9DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8269215-B2 | Pyromellitic diimide organic semiconductors and devices | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-09-18 | — | — | US | disclosed |
| US-8269215-B2 | Pyromellitic diimide organic semiconductors and devices | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-09-18 | — | — | US | disclosed |
| US-20110163301-A1 | PYROMELLITIC DIIMIDE ORGANIC SEMICONDUCTORS AND DEVICES | THE JOHNS HOPKINS UNIVERSITY (US) | 2011-07-07 | — | — | US | disclosed |
| US-20110163301-A1 | PYROMELLITIC DIIMIDE ORGANIC SEMICONDUCTORS AND DEVICES | THE JOHNS HOPKINS UNIVERSITY (US) | 2011-07-07 | — | — | US | disclosed |
| WO-2010011658-A2 | PYROMELLITIC DIIMIDE ORGANIC SEMICONDUCTORS AND DEVICES | THE JOHNS HOPKINS UNIVERSITY (US) | 2010-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110163301-A1 | PYROMELLITIC DIIMIDE ORGANIC SEMICONDUCTORS AND DEVICES | AQP4, FTO, KCNE1 | CA12 452/4885CA1 893/4885CA2 359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.