Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAPDH | P04406 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8732840 | 1.00 | GAPDH (0.53) | GAPDHALDH1A1GLAF2HPGD | |
| SCHEMBL8735796 | 0.95 | GAPDH (0.49) | GAPDHALDH1A1GLANPC1RAB9A | |
| SCHEMBL7937480 | 0.88 | CYP1A2 (0.46) | PLGPLAUPLATSMN1; SMN2NPC1 | |
| SCHEMBL5045934 | 0.83 | CA12 (0.49) | GAPDHALDH1A1GLAF2HPGD | |
| SCHEMBL9054823 | 0.79 | CYP1A2 (0.52) | ALDH1A1HPGDPLAUSMN1; SMN2NPC1 | |
| SCHEMBL26009136 | 0.78 | LMNA (0.59) | GAPDHALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27822793 | 0.78 | DYRK1A (0.39) | SMN1; SMN2NPC1RAB9ATP53CYP3A4 | |
| SCHEMBL27822808 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2NPC1RAB9ATP53MEN1 | |
| SCHEMBL27802178 | 0.77 | CYP1A2 (0.46) | PLAUSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL253760 | 0.77 | GLA (0.65) | GAPDHALDH1A1GLAF2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826680-A1 | Dihydronaphthalene and naphthalene compounds, intermediates, formulations, and methods | ELI LILLY AND COMPANY (US) | 1998-03-04 | — | — | EP | disclosed |