Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.34 |
| ▸ | F2 | P00734 | 3/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8732904 | 0.93 | NFE2L2 (0.33) | ALDH1A1L3MBTL1HSD11B1F2NR3C1 | |
| SCHEMBL8730136 | 0.92 | PTK2 (0.36) | ALDH1A1L3MBTL1HSD11B1F2NR3C1 | |
| SCHEMBL8734740 | 0.87 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1TSHRSMN1; SMN2HSD11B1 | |
| SCHEMBL8764166 | 0.86 | HSD11B1 (0.33) | HSD11B1F2NR3C1NFE2L2PGR | |
| SCHEMBL8734981 | 0.86 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1HSD11B1F2NR3C1 | |
| SCHEMBL8734923 | 0.84 | SMN1; SMN2 (0.38) | ALDH1A1L3MBTL1TSHRSMN1; SMN2NR3C1 | |
| SCHEMBL8730056 | 0.83 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1TSHR | |
| SCHEMBL8731843 | 0.82 | HSD17B10 (0.37) | ALDH1A1HSD11B1F2NFE2L2PGR | |
| SCHEMBL8764065 | 0.82 | HSD11B1 (0.33) | HSD11B1F2NFE2L2KCNH2 | |
| SCHEMBL8764592 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699390-B1 | Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use | ROHM & HAAS (US) | 1998-10-07 | — | — | EP | claimed |