SCHEMBL8734740

SCHEMBL8734740

CC(C)OP(C)(=O)COS(=O)(=O)c1ccccc1Cl

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HSD11B1 P28845 4/20 0.33
F2 P00734 3/20 0.32
NR3C1 P04150 1/20 0.32
PGR P06401 1/20 0.32
KCNH2 Q12809 1/20 0.32
NFE2L2 Q16236 1/20 0.32
PRSS2 P07478 1/20 0.32
HTR6 P50406 1/20 0.32
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ITGAV P06756 1/20 0.32
KDM4E B2RXH2 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8734748 0.87 ALDH1A1 (0.36) ALDH1A1L3MBTL1HSD11B1F2NR3C1
SCHEMBL8762833 0.86 HSD11B1 (0.35) HSD11B1F2NR3C1PGRKCNH2
SCHEMBL8734981 0.85 ALDH1A1 (0.34) ALDH1A1L3MBTL1HSD11B1F2NR3C1
SCHEMBL8732325 0.84 TSHR (0.34) ALDH1A1L3MBTL1NR3C1PGRTSHR
SCHEMBL8734720 0.84 ALDH1A1 (0.40) ALDH1A1L3MBTL1TSHRKDM4E
SCHEMBL8732904 0.84 NFE2L2 (0.33) ALDH1A1L3MBTL1HSD11B1F2NR3C1
SCHEMBL8730136 0.83 PTK2 (0.36) ALDH1A1L3MBTL1HSD11B1F2NR3C1
SCHEMBL8732839 0.81 ALDH1A1 (0.33) ALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL8734645 0.80 NR3C1 (0.35) L3MBTL1NR3C1TSHRSMN1; SMN2
SCHEMBL8732229 0.80 MEN1 (0.38) HSD11B1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP claimed
US-5500405-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1996-03-19 US claimed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP claimed
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP disclosed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP disclosed