Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.51 |
| ▸ | DRD4 | P21917 | 10/20 | 0.51 |
| ▸ | DRD3 | P35462 | 10/20 | 0.51 |
| ▸ | DRD1 | P21728 | 8/20 | 0.51 |
| ▸ | DRD5 | P21918 | 8/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9956909 | 0.88 | DRD2 (0.62) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL4096013 | 0.86 | DRD2 (0.64) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL23467151 | 0.81 | DRD2 (0.50) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL16926997 | 0.81 | DRD2 (0.41) | DRD2DRD4DRD3DRD1DRD5 | |
| Hydrogen Sulfide SCHEMBL29924299 | 0.80 | DRD2 (0.49) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL22444937 | 0.80 | DRD2 (0.60) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL7023211 | 0.80 | DRD2 (0.42) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL28166225 | 0.75 | PTGS2 (0.41) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL367003 | 0.75 | DRD2 (0.42) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL10182018 | 0.75 | DRD3 (0.52) | DRD2DRD4DRD3DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697387-B1 | Improved method for the preparation of iodonium salts | DOW CORNING (US) | 1998-04-22 | — | — | EP | disclosed |