Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10456973 | 0.90 | CYP3A4 (0.47) | L3MBTL1KDM4ECYP3A4ACHERXRA | |
| SCHEMBL4847226 | 0.87 | RXRA (0.47) | L3MBTL1RXRARXRBALDH1A1MAPK1 | |
| SCHEMBL27685454 | 0.81 | PTGS1 (0.40) | L3MBTL1KDM4ECYP3A4ACHERXRA | |
| SCHEMBL27704418 | 0.81 | ALDH1A1 (0.46) | L3MBTL1KDM4ECYP3A4ACHERXRA | |
| SCHEMBL27704419 | 0.81 | CYP3A4 (0.40) | L3MBTL1KDM4ECYP3A4ACHERXRA | |
| SCHEMBL5632184 | 0.80 | METAP2 (0.42) | L3MBTL1RXRARXRBALDH1A1MAPK1 | |
| SCHEMBL9871803 | 0.78 | KDM4E (0.44) | L3MBTL1KDM4ECYP3A4ACHEALDH1A1 | |
| SCHEMBL4520339 | 0.78 | KDM4E (0.44) | L3MBTL1KDM4ECYP3A4ACHEALDH1A1 | |
| SCHEMBL15730488 | 0.78 | SHBG (0.44) | L3MBTL1KDM4ECYP3A4ACHEALDH1A1 | |
| SCHEMBL27629673 | 0.76 | CYP3A4 (0.42) | L3MBTL1KDM4ECYP3A4ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706987-B1 | Process for preparing alkylated aromatic carboxylic acids and carboxylic acid halogenides | CIBA GEIGY AG (CH) | 1998-06-03 | — | — | EP | disclosed |
| CN-1129211-A | Process for the preparation of alkylated aromatic carboxylic acids and acyl halides | CIBA GEIGY AG (CH) | 1996-08-21 | — | — | CN | disclosed |