SCHEMBL8735442

SCHEMBL8735442

NSc1nc2c(C3CCCCC3)c(S)ccc2s1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
TXN P10599 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL357736 0.75 TXN (0.39) ALDH1A1HPGDTDP1CYP1A2CYP2D6
SCHEMBL4443518 0.72 ALDH1A1 (0.31) ALDH1A1
SCHEMBL11665005 0.69 CYP1A2 (0.41) ALDH1A1HPGDTDP1CYP1A2CYP2D6
SCHEMBL2046979 0.68 PSMD14 (0.36) ALDH1A1HPGDTDP1CYP1A2CYP2D6
SCHEMBL8735444 0.68 TXN (0.43) ALDH1A1HPGDTDP1CYP1A2CYP2D6
SCHEMBL28286521 0.66 LMNA (0.41) ALDH1A1TDP1
SCHEMBL27784528 0.65 TXN (0.56) ALDH1A1HPGDTDP1CYP1A2CYP2D6
SCHEMBL5205910 0.63
SCHEMBL21072843 0.63 NPC1 (0.33) ALDH1A1HPGDTDP1
SCHEMBL7055244 0.62 ALDH1A1 (0.65) ALDH1A1HPGDTDP1CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0680997-B1 Rubber compositions containing sulfur-bearing organosilicon compounds BAYER AG (DE) 1998-09-30 EP disclosed
EP-0680997-A1 Rubber compositions containing sulfur-bearing organosilicon compounds BAYER AG (DE) 1995-11-08 EP disclosed