Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 5/20 | 0.61 |
| ▸ | PSMB11 | A5LHX3 | 9/20 | 0.49 |
| ▸ | PSMA7 | O14818 | 9/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 9/20 | 0.49 |
| ▸ | PSMA1 | P25786 | 9/20 | 0.49 |
| ▸ | PSMA2 | P25787 | 9/20 | 0.49 |
| ▸ | PSMA3 | P25788 | 9/20 | 0.49 |
| ▸ | PSMA4 | P25789 | 9/20 | 0.49 |
| ▸ | PSMB8 | P28062 | 9/20 | 0.49 |
| ▸ | PSMB9 | P28065 | 9/20 | 0.49 |
| ▸ | PSMA5 | P28066 | 9/20 | 0.49 |
| ▸ | PSMB4 | P28070 | 9/20 | 0.49 |
| ▸ | PSMB6 | P28072 | 9/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 9/20 | 0.49 |
| ▸ | PSMB10 | P40306 | 9/20 | 0.49 |
| ▸ | PSMB3 | P49720 | 9/20 | 0.49 |
| ▸ | PSMB2 | P49721 | 9/20 | 0.49 |
| ▸ | PSMA6 | P60900 | 9/20 | 0.49 |
| ▸ | PSMA8 | Q8TAA3 | 9/20 | 0.49 |
| ▸ | PSMB7 | Q99436 | 9/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945567 | 0.91 | CTSD (0.53) | CTSDPSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL8945683 | 0.89 | CTSD (0.52) | CTSDPSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL8945246 | 0.88 | CTSD (0.53) | CTSDPSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL7423701 | 0.88 | CTSD (0.51) | CTSDPSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL9095899 | 0.88 | CTSD (0.53) | CTSDPSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL8041703 | 0.86 | CTSD (0.49) | CTSDPSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL7807985 | 0.84 | CTSD (0.56) | CTSDPSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL8736216 | 0.84 | CTSD (0.53) | CTSDPSMB1PSMB8PSMB9PSMB5 | |
| SCHEMBL7807979 | 0.84 | TRPM8 (0.56) | CTSDPSMB1TRPM8CTSSCTSK | |
| SCHEMBL7421386 | 0.83 | CTSD (0.48) | CTSDPSMB11PSMA7PSMB1PSMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716973-A | ADMINISTERING DIFLUORO STATONE ANALOGS | MERRELL PHARMACEUTICALS INC. (US) | 1998-02-10 | — | — | US | disclosed |
| US-5559140-A | VIRICIDES | MERRELL PHARMACEUTICALS INC. (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0565631-B1 | ANTI-VIRAL COMPOUNDS | MERRELL PHARMA INC (US) | 1996-09-18 | — | — | EP | disclosed |
| EP-0565631-A1 | ANTI-VIRAL COMPOUNDS. | MERRELL DOW PHARMA (US) | 1993-10-20 | — | — | EP | disclosed |
| WO-1992012123-A1 | ANTI-VIRAL COMPOUNDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-07-23 | — | — | WO | disclosed |